What do we currently know about the clinically isolated syndrome suggestive of multiple sclerosis? An update

T Grzegorski, J Losy - Reviews in the Neurosciences, 2020 - degruyter.com
… also include isolated brainstem syndromes, cerebellar involvement, … Prediction based on
machine learning techniques is very … of conversion to MS is to estimate the risk of the disease

Cerebellar and/or brainstem lesions indicate poor prognosis in multiple sclerosis: a systematic review

Y Yang, M Wang, L Xu, M Zhong, Y Wang… - Frontiers in …, 2022 - frontiersin.org
… and the progression of clinically isolated syndromes (CIS) to … CIS has a higher risk of early
conversion to MS (HR, 2.0; 95% … have no statistical significance for predicting prognosis (18, …

[HTML][HTML] Evaluating magnetic resonance diffusion properties together with brain volumetry may predict progression to multiple sclerosis

J Stulík, M Keřkovský, M Kuhn, M Svobodová… - Academic …, 2022 - Elsevier
DTI parameters together with brain volumetry in patients with early-stage CIS may be useful
in predicting conversionClinically isolated syndrome (CIS) is a monophasic clinical episode …

[HTML][HTML] MRI prognostic factors in multiple sclerosis, neuromyelitis optica spectrum disorder, and myelin oligodendrocyte antibody disease

R Cortese, A Giorgio, G Severa… - Frontiers in Neurology, 2021 - frontiersin.org
… In patients with the clinically isolated syndrome (CIS), a higher number … non-lesional tissue
and along specific WM tracts (71, 72). These techniques include diffusion tensor imaging (DTI

MRI biomarkers of disease progression and conversion to secondary-progressive multiple sclerosis

E Tavazzi, R Zivadinov, MG Dwyer… - Expert Review of …, 2020 - Taylor & Francis
… , both within focal lesions and in the non-lesional tissue of both … with a so-called
clinically isolated syndrome, and is a … in this regard than traditional DTI-based measures [Citation113]. …

[HTML][HTML] MRI biomarkers of disease progression in multiple sclerosis: old dog, new tricks?

Y Barnett, JY Garber, MH Barnett - Quantitative Imaging in …, 2020 - ncbi.nlm.nih.gov
… MS/CIS patients with conversion to disability progression compared to … in a cohort of patients
with clinically isolated syndrome (CIS) and MS. … metrics, such change in lesion DTI or MTR. …

Patterns of brain atrophy in recently-diagnosed relapsing-remitting multiple sclerosis

R Meijboom, EN York, A Kampaite, MA Harris… - PLoS …, 2023 - journals.plos.org
… image with a rigid body transformation (degrees of freedom = … with clinical changes in clinical
isolated syndrome (CIS) or … (DTI) to explore cerebellar changes in RRMS have observed …

[HTML][HTML] Multiple sclerosis and subclinical neuropathology in healthy individuals with familial risk: A scoping review of MRI studies

M Mortazavi, Ö Hizarci, LA Gerdes, J Havla… - NeuroImage: Clinical, 2021 - Elsevier
… risk for patients with radiologically isolated syndrome (RIS) to … FA indices of DTI, and the
RNFL and TMV measures of OCT … damage in non-lesional NAWM of patients with MS from …

Multiple sclerosis diagnosis using machine learning and deep learning: challenges and opportunities

N Aslam, IU Khan, A Bashamakh, FA Alghool… - Sensors, 2022 - mdpi.com
patients; third, in predicting the transformation of the diseaseinto patients with radiologically
isolated syndrome (RIS), … extra information like lesion location, non-lesional white matter, …

Peripapillary vessel density as early biomarker in multiple sclerosis

G Cennamo, A Carotenuto, D Montorio… - Frontiers in …, 2020 - frontiersin.org
… between the retinal impairment and brain atrophy on MRI, … disease pathogenesis. Feucht
et al. recently studied retinal vasculature network in patients with clinically isolated syndrome (…